Spear RC (in press), Expert Commentary on Integration of Water, Sanitation, and Hygiene for the Prevention and Control of Neglected Tropical Diseases: A Rational for Inter-Sectoral Collaboration:  Can the control of neglected tropical diseases profit from a good WASH? PLoS Neglected Tropical Diseases.

Carlton EJ, Hubbard A, Wang  S, Spear RC (2013). Repeated Schistosoma japonicum Infection Following Treatment in Two Cohorts: Evidence for Host Susceptibility to Helminthiasis? PLoS Neglected Tropical Diseases, 7(3), e2098.

Wang S, Carlton, EJ, Chen L, Liu Y, Spear RC (2013). Evaluation of an educational intervention on villagers’ knowledge, attitude and behaviour regarding transmission of Schistosoma japonicum in Sichuan province, China. Acta Tropica, 127(3), 226-235.

Xiao N, Remais JV, Brindley PJ, Qiu DC, Carlton EJ, Li RZ, . . . Blair D. (2013). Approaches to genotyping individual miracidia of Schistosoma japonicum. Parasitology Research, 112(9).

Dhingra R, Jimenez V, Chang H, Gambhir M, Liu Y, Remais J. Spatially-explicit simulation modeling of ecological response to climate change: methodological considerations in predicting shifting population dynamics of infectious disease vectors, ISPRS International Journal of Geo-Information, 2(3):645-664, 2013.

Schrader M, Hauffe T, Zhang Z, Davis G, Jopp F, Remais J, Wilke T. Spatially explicit modeling of schistosomiasis risk in eastern China based on a synthesis of epidemiological, environmental and intermediate host genetic data, PLoS Neglected Tropical Diseases, 7(7):e2327, 2013.

Wu J, Dhingra R, Gambhir M, Remais J. Sensitivity analysis of infectious disease models: methods, advances and their application, Journal of the Royal Society Interface, 10(86), 2013.

Lam H-M, Remais J, Fung M-C, Xu L, Sun SS. Food supply and food safety in China, The Lancet, 381(9882):2044-2053, 2013.

Remais J, Zeng G, Li G, Tian L, Engelgau M. Convergence of non-communicable and infectious diseases in low- and middle-income countries, International Journal of Epidemiology, 42(1): 221-227, 2013.


Fung MS, Xiao N, Wang S, Carlton EJ (2012) Field evaluation of a PCR test for Schistosoma japonicum egg detection in low-prevalence regions of China. Am J Trop Med Hyg 87:1053-8.

Remais J, Zeng G, Li G, Tian L, Engelgau M (2012) Convergence of non-communicable and infectious diseases in low- and middle-income countries. International Journal of Epidemiology.

Moore J, Liang S, Akullian A, Remais J (2012) Cautioning the use of degree-day models for climate change projections: predicting the future distribution of parasite hosts in the presence of parametric uncertainty. Ecological Applications.

Akullian A, Lu D, McDowell J, Davis G, Spear R, Remais J (2012) Modeling the combined influence of host dispersal and waterborne fate and transport on pathogen spread in complex landscapes. Water Quality, Exposure and Health 4(3):159-168.

Carlton EJ, Liang S, McDowell JZ, Li H, Luo W, Remais JV (2012) Regional disparities in the burden of disease attributable to unsafe water and poor sanitation in China. Bull World Health Organ 90:578-587.

Remais J, Eisenberg J (2012) Balance between clinical and environmental responses to infectious diseases. Lancet 379:1457-9.

Spear RC (2012) Internal versus external determinants of Schistosoma japonicum transmission in irrigated agricultural villages. J R Soc Interface 9:272-82. doi 10.1098.

Gong P, Liang S, Carlton EJ, Jiang Q, Wu J,Wang L, Remais JV. (2012) Urbanisation and health in China. Lancet 379: 843-852.


Hauswald AK, Remais J, Xiao N, Davis GM, Ding L, Bale MJ, Wilke T (2011) Stirred, not shaken: genetic structure of the intermediate snail host Oncomelania hupensis robertsoni in an historically endemic schistosomiasis area. Parasites & Vectors, 4:206.

Seto EYW, Remais JV, Carlton EJ, Wang S, Liang S, Brindley PJ, Qiu D, Spear RC, Wang L, Wang T, Chen H, Dong X, Wang L, Hao Y, Bergquist R, Zhou X (2011) Toward sustainable and comprehensive control of schistosomiasis in China: lessons from Sichuan. PLoS Negl Trop Dis 5: e1372.

Spear RC, Seto EYW, Carlton EJ, Liang S, Remais JV, Zhong B, Qiu D (2011)  The challenge of surveillance in moving from low transmission to elimination of schistosomiasis in China. Int J Parasitol 41:1243-1247.

Spear RC and Liang S (2011) Mathematical modeling as an aid in developing strategy for sustainable interruption of S. japonicum transmission in the hilly and mountainous regions of China. [In Chinese] Chinese journal of schistosomiasis control 23: 231-236.

Carlton EJ, Bates MN, Zhong B, Seto EY, Spear RC (2011) Evaluation of Mammalian and Intermediate Host Surveillance Methods for Detecting Schistosomiasis Reemergence in Southwest China. PLoS Negl Trop Dis 5: e987.

Seto EYW, Wong BK, Lu D, Zhong B (2011) Human schistosomiasis resistance to praziquantel in China: Should We Be Worried? Am J Trop Med Hyg 85: 74-82.

Stothard JR, Sousa-Figueiredo JC, Betson M, Seto EYW, Kabatereine NB (2011) Investigating the spatial micro-epidemiology of diseases within apoint-prevalence sample: a field applicable method for rapid mapping of households using low-cost GPS-dataloggers. Trans R Soc Trop Med Hyg, doi:10.1016/j.trstmh.2011.05.007

Dhingra R, Christensen ER, Liu Y, Zhong B, Wu CF, et al. (2011) Greenhouse gas emission reductions from domestic anaerobic digesters linked with sustainable sanitation in rural China. Environ Sci Technol 45: 2345-2352.

Remais JV, Xiao N, Akullian A, Qiu D, Blair L (2011) Genetic Assignment Methods for Gaining Insight into the Management of Infectious Disease by Understanding Pathogen, Vector, and Host Movement. PLoS Pathogens 7: e1002013.

Worrell C, Xiao N, Vidal JE, Chen L, Zhong B, et al. (2011) Field detection of Schistosoma japonicum cercariae in environmental water samples by quantitative PCR. Appl Environ Microbiol 77: 2192-2195.

Xiao N, Remais J, Brindley PJ, Qiu D, Spear R, et al. (2011) Polymorphic microsatellites in the human bloodfluke, Schistosoma japonicum, identified using a genomic resource. Parasit Vectors 4: 13.

Zhang Yi,Zhang Xu-dong, Zhong Bo,et al. (2011) Evaluation of Disease Burden of Schistosomiasis in Sichuan Province. [In Chinese] Journal of Preventive Medicine Information 27: 271-273.

Zhong B, Wu ZS, Chen L, Liang S, Dong XQ, Qiu DC (2011) Strengthening the achievements of schistosomiasis control in hilly regions of China. [In Chinese] Chinese journal of schistosomiasis control 23: 10-13.

Zhu HQ, Zhang GR, Zhong B, Tang SG, Cao CL, Jia B, Zhang Y, Li JG, Fu T, Bao, ZP (2011) Toxicity of niclosamide with plastic film mulching to fish. [In Chinese] Chinese journal of schistosomiasis control 23: 38-41.

Zhu HQ, Zhong B, Zhang GR, Tang SG, Cao CL, Zhang XD, Jia B, Zhang Y, Li JG, Fu T, Chen L, Lu D, Bao ZP (2011) Molluscicidal effect of film on ditches in mountainous schistosomiasis endemic regions. [In Chinese] Chinese journal of schistosomiasis control 23: 128-132.


Carlton EJ, Hsiang M, Zhang Y, Johnson S, Hubbard A, et al. (2010) The impact of Schistosoma japonicum infection and treatment on ultrasound-detectable morbidity: a five-year cohort study in Southwest China. PLoS Negl Trop Dis 4: e685.

Gambhir M, Bockarie M, Tisch D, Kazura J, Remais J, et al. (2010) Geographic and ecologic heterogeneity in elimination thresholds for the major vector-borne helminthic disease, lymphatic filariasis. BMC Biol 8: 22.

Hsiang MS, Carlton EJ, Zhang Y, Zhong B, Qiu D, et al. (2010) Use of Ultrasonography to Evaluate Schistosoma japonicum-related Morbidity in Children, Sichuan Province, China, 2000–2007. Am J Trop Med Hyg 82: 103-111.

Liu Yang , Luan Rongsheng, Zhong Bo; et al. (2010) Determinants of Re-merging of Schistosomiasis Epidemic in Areas with Transmisson Once Controlled in Sichuan Province. [In Chinese] Journal of Preventive Medicine Information 26: 165-169.

Remais J (2010) Modelling environmentally-mediated infectious diseases of humans: transmission dynamics of schistosomiasis in China. In: Michael E, Spear RC, editors. Modelling Parasite Transmission and Control. New York: Landes Bioscience and Springer Science+Business Media. pp. 79-98.

Remais J, Akullian A, Ding L, Seto E (2010) Analytical methods for quantifying environmental connectivity for the control and surveillance of infectious disease spread. J R Soc Interface 7: 1181-1193.

Seto EY, Carlton EJ (2010) Disease transmission models for public health decision-making: designing intervention strategies for Schistosoma japonicum. In: Michael E, Spear RC, editors. Advances in experimental medicine and biology. New York: Landes Bioscience and Springer Science+Business Media. pp. 172-183.

Spear RC, Hubbard A (2010) Parameter estimation and site-specific calibration of disease transmission models. In: Michael E, Spear RC, editors. Modelling Parasite Transmission and Control. New York: Landes Bioscience and Springer Science+Business Media. pp. 99-111.

Sudat SE, Carlton EJ, Seto EY, Spear RC, Hubbard AE (2010) Using variable importance measures from causal inference to rank risk factors of schistosomiasis infection in a rural setting in China. Epidemiol Perspect Innov 7: 3.


Gurarie D, Seto EY (2009) Connectivity sustains disease transmission in environments with low potential for endemicity: modelling schistosomiasis with hydrologic and social connectivities. J R Soc Interface 6: 495-508.

Remais J, Chen L, Seto E (2009) Leveraging rural energy investment for parasitic disease control: schistosome ova inactivation and energy co-benefits of anaerobic digesters in rural China. PLoS One 4: e4856.

Remais J, Zhong B, Carlton EJ, Spear RC (2009) Model approaches for estimating the influence of time-varying socio-environmental factors on macroparasite transmission in two endemic regions. Epidemics 1: 213-220.

Chen L, Zhong B, Qiu DQ et al. (2009) Analysis on Knowledge, Attitude, Practice of Schistosomiasis Control of Population in Endemic Areas of Sichuan. [In Chinese] Journal of Preventive Medicine Information 25: 416-419.


Hung YW, Remais J (2008) Quantitative detection of Schistosoma japonicum cercariae in water by real-time PCR. PLoS Negl Trop Dis 2: e337.

Liang S, Spear RC (2008) Model-Based Insights into Multi-Host Transmission and Control of Schistosomiasis. PLoS Med 5: e23.

Remais J, Liang S, Spear RC (2008) Coupling hydrologic and infectious disease models to explain regional differences in schistosomiasis transmission in southwestern China. Environmental Science & Technology 42: 2643-2649.

Zhong B, Kang JX, Yin ZC, et al. (2008) Evaluation of Schistosomiasis Control Effect in Sichuan Province. [In Chinese] Journal of Preventive Medicine Information 24: 414-417.


Liang S, Seto EY, Remais JV, Zhong B, Yang C, et al. (2007) Environmental effects on parasitic disease transmission exemplified by schistosomiasis in western China. Proc Natl Acad Sci U S A 104: 7110-7115.

Remais J, Hubbard A, Wu ZS, Spear RC (2007) Weather-driven dynamics of an intermediate host: mechanistic and statistical population modelling of Oncomelania hupensis. Journal of Applied Ecology 44: 781-791.

Seto EY, Knapp F, Zhong B, Yang C (2007) The use of a vest equipped with a global positioning system to assess water-contact patterns associated with schistosomiasis. Geospat Health 1: 233-241.

Seto EY, Lee YJ, Liang S, Zhong B (2007) Individual and village-level study of water contact patterns and Schistosoma japonicum infection in mountainous rural China. Trop Med Int Health 12: 1199-1209.

Seto EYW, Moore CG, Hoskins R (2007) Geographic Information Systems and Remote Sensing for Infectious Disease Surveillance. In: M’ikanatha N, Lynfield R, Van Beneden CA, de Valk H, editors. Infectious Disease Surveillance. London: Blackwell.

Zhu HQ, Zhong B, Cao CL, et al. (2007) Molluscicidal effect of Rongbao Powder in schistosomiasis mountainous areas. [In Chinese] Chinese Journal of Schistosomiasis Control 19: 212-216.


Liang S, Yang C, Zhong B, Qiu D (2006) Re-emerging schistosomiasis in hilly and mountainous areas of Sichuan, China. Bull World Health Organ 84: 139-144.

Spear RC, Seto E, Remais J, Carlton EJ, Davis G, et al. (2006) Fighting waterborne infectious diseases. Science 314: 1081-1083.

Xu B, Gong P, Seto E, Liang S, Yang CH, et al. (2006) A spatial-temporal model for assessing the effects of intervillage connectivity in schistosomiasis transmission. Annals of the Association of American Geographers 96: 31-46.

Zhong B, Liang S, Zhang Y, Lai YH, Chen L, Yin HZ, Zhao YM, Lu JQ, Qiu DC. (2006) Water exposure modes and times of different populations in mountainous schistosomiasis endemic areas near Qionghai lake. [In Chinese] Chinese journal of preventive medicine 40: 239-243.

Zhong B, et al. (2006) The study of the relationship among three indexes of endemic water exposure and prevalence of schistosomiasis in mountainous type. [In Chinese] Chinese Journal of Public Health 22: 1075-1077.

Zhong B, Gong Q, et al. (2006) Status of schistosomiasis control effects and longitudinal observation on impact of integrated control of Pujiang County, Sichuan Province. Journal of  Parasitizes and Infectious Diseases 4: 59-62.


Driscoll AJ, Kyle JL, Remais J (2005) Development of a novel PCR assay capable of detecting a single Schistosoma japonicum cercaria recovered from Oncomelania hupensis. Parasitology 131: 497-500.

Liang S, Spear RC, Seto E, Hubbard A, Qiu D (2005) A multi-group model of Schistosoma japonicum transmission dynamics and control: model calibration and control prediction. Trop Med Int Health 10: 263-278.

Lowe D, Xi J, Meng X, Wu Z, Qiu D, et al. (2005) Transport of Schistosoma japonicum cercariae and the feasibility of niclosamide for cercariae control. Parasitol Int 54: 83-89.

Qiu DC, Hubbard AE, Zhong B, Zhang Y, Spear RC (2005) A matched, case-control study of the association between Schistosoma japonicum and liver and colon cancers, in rural China. Ann Trop Med Parasitol 99: 47-52.

Seto EY, Zhong B, Kouch J, Hubbard A, Spear RC (2005) Genetic and household risk factors for Schistosoma japonicum infection in the presence of larger scale environmental differences in the mountainous transmission areas of China. Am J Trop Med Hyg 73: 1145-1150.


Spear RC, Seto E, Liang S, Birkner M, Hubbard A, et al. (2004) Factors influencing the transmission of Schistosoma japonicum in the mountains of Sichuan province of China. Am J Trop Med Hyg 70: 48-56.

Spear RC, Zhong B, Mao Y, Hubbard A, Birkner M, et al. (2004) Spatial and temporal variability in schistosome cercarial density detected by mouse bioassays in village irrigation ditches in Sichuan, China. Am J Trop Med Hyg 71: 554-557.

Wu Z, Zhao L, Mao Y, Yin H, Wong H, et al. (2004) Report on Oncomelania Snail Surveys in Ditches in the Basin Around Qionghai Lake, Xichang, Sichuan [in Chinese]. Chin J Schisto Control 5: 359-362.

Xu B, Gong P, Biging G, Liang S, Seto E, et al. (2004) Snail density prediction for schistosomiasis control using ikonos and ASTER images. Photogrammetric Engineering and Remote Sensing 70: 1285-1294.


Davis G, Wu W, Liu H, Williams A, Lu S, et al. (2003) Applying GIS and RS to the epidemiology of schistsomiasis in Poyang Lake, China. Geographic Information Sciences 8: 67-77.

Xu B, Gong P, Seto E, Spear R (2003) Comparison of gray-level reduction and different texture spectrum encoding methods for land-use classification using a panchromatic ikonos image. Photogrammetric Engineering and Remote Sensing 69: 529-536.


Hubbard A, Liang S, Maszle D, Qiu D, Gu X, et al. (2002) Estimating the distribution of worm burden and egg excretion of Schistosoma japonicum by risk group in Sichuan province, China. Parasitology 125: 221-231.

Liang S, Maszle D, Spear RC (2002) A quantitative framework for a multi-group model of Schistosomiasis japonicum transmission dynamics and control in Sichuan, China. Acta Trop 82: 263-277.

Seto EYW, Wu WP, Qiu DC, Liu HY, Gu XG, et al. (2002) Impact of soil chemistry on the distribution of Oncomelania hupensis (Gastropoda : Pomatiopsidae) in China. Malacologia 44: 259-272.

Seto E, Xu B, Liang S, Gong P, Wu WP, et al. (2002) The use of remote sensing for predictive modeling of schistosomiasis in China. Photogrammetric Engineering and Remote Sensing 68: 167-174.

Spear RC, Hubbard A, Liang S, Seto E (2002) Disease transmission models for public health decision making: toward an approach for designing intervention strategies for Schistosomiasis japonica. Environ Health Perspect 110: 907-915.

Stothard JR, Mgeni AF, Khamis S, Seto E, Ramsan M, et al. (2002) New insights into the transmission biology of urinary schistosomiasis in Zanzibar. Trans R Soc Trop Med Hyg 96: 470-475.

Wu WP, Davis G, Seto E, Zhang J, Hua J, et al. (2002) Application of remote sensing for surveillance of snail habitats in Poyang Lake, China. Chinese J Parasitology and Parasitic Disease 20: 205-208, in Chinese.


Chen L, Zhong B, Sha KY, Zhao LG, Ying HZ, et al. (2001) Geographical and agricultural characteristics and prevalence of schistosomiasis around Qionghai Lake Area, Xichang City, Sichuan. Journal of Practical Parasitic Diseases 9: 145-148, in Chinese.

Liang YS, Dai JR, Ning A, Yu DB, Xu XJ, et al. (2001) Susceptibility of Schistosoma japonicum to praziquantel in China. Trop Med Int Health 6: 707-714.

Seto E, Liang S, Qiu D, Gu X, Spear RC (2001) A protocol for geographically randomized snail surveys in schistosomiasis fieldwork using the global positioning system. Am J Trop Med Hyg 64: 98-99.

2000 and earlier

Spear RC, Gong P, Seto E, Zhou Y, Xu B, et al. (1999) Remote sensing and GIS for schistosomiasis control in mountainous areas in Sichuan, China. Geographic Info Sci 4: 14-22.

Zhou Y, Maszle D, Spear RC, Gong P, Gu X, et al. (1999) GIS and spatial analysis in schistosomiasis transmission and control in mountainous areas. Chinese J Schistosomiasis Control 11: 263-266, in Chinese.

Maszle DR, Whitehead PG, Johnson RC, Spear RC (1998) Hydrological studies of schistosomiasis transport in Sichuan Province, China. Sci Total Environ 216: 193-203.

Zhou Y, Maszle D, Gong P, Spear RC, Gu X (1996) GIS based spatial network models of schistosomiasis infection. Geographic Info Sci 2: 51-57.